RFID real-time tracking MacDek Shengke makes the information of surrogate animals zero missed
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MacDerkey Life Science Research Institute (hereinafter referred to as MacDerKe Bioscience), which is affiliated to MacDerKe Biotechnology Co., Ltd., is mainly engaged in accepting the safety and functionality of health food companies, medical equipment companies and biotech product companies. The R&D test commission is one of the few research institutions in Taiwan that has passed TAF (ISO 17025) and actively applied for Good Laboratory Practice (GLP) of the “Department of Health, Executive Yuan”. Simplify the feeding management and form records in the laboratory and comply with the operating procedures and specifications of each link of the ISO and GLP laboratories to ensure the correctness of the experimental results and other requirements, so that the feeding management process can be managed by the e-system. The goal pursued by McDecker.
Hong Zhijun, general manager of Macdcare Biotechnology, said that with the high development of the biotechnology industry and the increase in business volume, the company has always hoped to improve the quality of animal care services through new technologies. The management mechanism is inspired by livestock-related applications. “RFID can be used to grasp the production history of agricultural and livestock products, so it must also be used in animal monitoring.” Think of models for various applications.
Use RFID to establish a household registration management system to master animal health with zero time difference
Due to its rich experience in animal testing and management, McDecker found that in most of the experiments, animals are grouped and then administered drugs and their health status and related information are observed and recorded. Therefore, the management mode for each breeding cage is the most suitable. In line with the actual cost effect and demand. Taking advantage of this feature, MacDecker Biotech has established RFID tags for all breeding rooms, breeding cages and breeding cages, just like the house number established by the household registration unit. Animal feeding records in each group.
Caption: Each breeding cage is equipped with an exclusive RFID door plate, which is convenient for breeders to record the health status of the group of experimental animals. (Provided by McDecker Biotech)
In order to report the results of animal monitoring to customers in real time, MacDerk Life Science has also built video monitoring equipment. Once an animal is found abnormal, the breeder will use the wireless IP Cam to capture the animal image, and then use the 3G network to capture the animal image. Send the message to the customer’s mobile phone. After receiving the message, the customer can directly contact the breeder and view the real-time image of the animal through the computer to further decide the response method. This “zero-day” monitoring mode can greatly reduce the number of non-breeders entering the animal center, reducing The risk of external contamination in the animal room and the rate of experimental errors, to avoid the risk of failure of animal experiments and the need to re-test.
In addition, the biggest benefit of this mechanism is to reduce the omission of manual management. The condition of the animal room is based on the records of the breeders and is managed manually. However, it is difficult for the entrusted breeding management unit to confirm the number of patrols and time points of the breeders. Distance scanning can grasp the reaction of animals after administration in the shortest time, and upload relevant data and images to the system. Customers can inquire through the dedicated webpage and fully grasp the progress of the experiment.
RFID records life course to maximize animal value
The biggest benefit of applying the new management mechanism is to make animal information transparent. MacDerke Biosciences has created a new concept of “idle animal management” on this system, and further established the “experimental animal sharing” system to achieve the principle of animal care. . That is to say, when an experiment is over, the animals that have not been sacrificed will be included in the idle area. In the past, because the information flow between the research hosts was not transparent, even if the research hosts were willing to share the resources of the experimental animals, it was difficult to do so within a limited time. Let the animal provide other experimental use, but directly sacrifice. However, with the assistance of RFID management, the process of each animal undergoing the experiment is recorded in the system in detail, and the research director can inquire about the previous drug administration status of the animals in the idle area. an experiment. Hong Zhijun said that the cost of animal experiments is high, and each animal often needs to spend several thousand yuan to ten thousand yuan in the experimental process. If the animal sharing mechanism can be implemented, it will have considerable economic benefits for general breeding management. And can achieve the spirit of the 3R of experimental animals.
With the design of the terminal database and operating system of the household registration management system, daily feeding and breeding management data are recorded on a daily basis. The relevant personnel and the entrusting unit of the experiment can see the breeding details of experimental animals such as blood collection, surgery, diet, clinical records, etc. from a single form. , which is more efficient than the previous situation where you had to read through a large volume of experimental report records to find the experimental process and original data page by page, and also increased the customer’s service satisfaction with MacDesk.
The application of RFID to animal management is not limited to household registration management. At present, Medkay Biotechnology is also trying to implant RFID chips on experimental animals to establish an identification system and to understand the adaptation status of animals to the chips in their bodies. Hong Zhijun said that these kinds of animal microchips are generally used in research related to animal behavior. Implanting active tags in a single animal enables full-time tracking.
Caption: Implanting an RFID chip into a single animal helps to observe animal behavior. (Provided by McDecker Biotech)
Continuous tuning of system functions in preparation for diffusion applications
McDecker’s major is animal management, and he has limited understanding of RFID-related technologies, but Hong Zhijun believes that as long as the application mode is clear enough, this is not a problem. Before deciding to import, MacDekay had a long internal discussion to clarify the requirements. Therefore, after contact with Baokang Technology, which specializes in RFID warehouse management systems, it was possible to “get it right”. The scientific and technological management of animal rooms is on track in a short period of time.
Summarizing the current experience, Hong Zhijun believes that although the cooperative manufacturers are very familiar with the warehouse management system, the management thinking of goods and animals is different after all. Generally speaking, a certain pattern must be followed in the management of cargo warehousing codes. However, since MacDerke Senke itself is an entrusted experimental institution certified by ISO 9001 and ISO 17025, different cases or customers have another set of coding rules. In order to solve this problem, after in-depth discussions, Biocomm Technology suggested that MacDeskeen choose blank and rewritable labels to make the animal numbering pattern more flexible.
Hong Zhijun believes that generally speaking, as long as the number of animals managed by a laboratory exceeds 500, the daily operation process is quite cumbersome, and manual login is prone to omissions. Therefore, many large research institutions are currently interested in this management mechanism. strong. It is understood that there are currently about 20 to 30 large-scale experimental animal rooms in Taiwan, all of which will be the goal of the diffusion and application of this management mechanism. And add a fool-proof mechanism in the interface, hoping to make the process of experiment establishment and breeding data file smoother. In the future, if this set of RFID management can be successfully applied to major domestic animal centers, it will not only conform to the international trend of animal care 3R, but also save and avoid data for animal experiments in Taiwan Province each year due to expired breeding and repeated experiments. Millions of dollars in R&D spending.
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