Talking about the construction plan of radio frequency RFID in the drug management system

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my country has a large market space for the application of RFID technology to achieve drug management. RFID has great application potential in drug anti-counterfeiting and tracking and supply chain management. After adopting RFID technology, since drugs are tracked in every link of sales, their electronic resumes are recorded in the electronic database in real time, which greatly guarantees The safety of drugs in the circulation link is improved. my country has a large market space for the application of RFID technology to achieve drug management.

Drug management

The technology and status quo of anti-counterfeiting of domestic drugs

At present, the anti-counterfeiting technologies of domestic drugs mainly include paper watermarking technology, ink technology, laser holographic image anti-counterfeiting technology, barcode technology and telephone code technology, etc. These technologies have low technological content, are easy to be copied, have a short service life, and are not anti-fouling. It cannot be distinguished if it is stained.

The World Health Organization estimates that 10% of the world’s drugs are counterfeit drugs, of which as high as 40% in developing countries, causing consumer confidence to fluctuate and post-consumer disputes, increasing lawsuits, and ineffective treatment of counterfeit drugs. , It will delay the patient’s optimal treatment time, increase medical expenses, and cause great waste. Therefore, in November 2004, the US Food and Drug Administration (FDA) proposed a feasibility study plan for the use of radio frequency identification technology (RFID) for drug management, mainly for drug labels, electronic records, and drug manufacturing, circulation, and use. Wait for the drug delivery process. The U.S. Food and Drug Administration (FDA) has instructed all pharmaceutical companies across the United States to label all drugs delivered to hospitals with barcodes to identify the types of drugs and single-use drugs.

In recent years, my country has made considerable progress in the modernization of management in the medical and health field. This is reflected in the fact that most of the medium-sized and above hospitals have adopted computer management and are developing from a single machine to a networked direction. However, compared with the international advanced level, my country’s medical and health management level is still lagging behind. How to adjust the pace of development of the medical and health system, improve its management mechanism, improve its own management level, make better use of the overall advantages of the hospital, increase economic efficiency and enhance competitiveness, are issues that need to be resolved urgently.

The application of the combination of radio frequency technology and network technology in logistics management has achieved initial success. The first and largest application in my country is the supervision of railway vehicles. The Ministry of Railways installed radio frequency identification cards on the heads of more than 550,000 vehicles under its jurisdiction to realize the lining management of the vehicles. The effect is very good. It not only reduces the management cost and improves the management level, but also significantly increases the economic benefits.

my country’s application of radio frequency technology to the management of drugs is still in the research stage. Through the above examples of successful applications, it can be seen that radio frequency technology will be the main body of drug management in the future, and it will bring huge social and economic benefits to drug management. The application of radio frequency identification (RFID) in drug management aims to use high-tech to achieve safety supervision of special drugs and chemical reagents, prevent counterfeit drugs, expired drugs, and illegal drugs from entering the market, and encourage “medical and patient personnel” to use drugs correctly and curb The occurrence of undesirable phenomena of driving up drug prices and monopolizing the drug market, and improving the monitoring of drug transportation and storage environmental conditions; drug manufacturers can also dynamically monitor drug flow and sales through this system, so as to adjust the production and inventory of drugs and improve their operations benefit.

Overall technical solution

The key technologies to be solved for the application of radio frequency identification (RFID) in drug management include: routing and network control; the realization of AES encryption technology; digital signature technology; the integrity and correctness of the protocol; the development of user interface specifications. On the basis of in-depth study of network protocol specifications and radio frequency identification technical specifications, the design and implementation of the entire network are completed by layered development and interfaces provided between layers. Solution: 1. Establish and apply radio frequency identification technology and network technology to establish a drug management platform; 2. Build an overall plan for drug management; 3. Network data reading and writing equipment composed of radio frequency identification technology and network single-chip microcomputer; 4. System software writing ; Fifth, the frequency setting adopted by the radio frequency identification card used in different special medicines. The idea is to implant an ID or IC card with a unique address code in the drug packaging, register the drug with the drug management database through radio frequency identification when the drug leaves the factory, and provide an identifier in the hospital or pharmacy for doctors and patients to check the authenticity of the drug and leave the factory. Date or read the drug usage and precautions. When the drug is sold and used, the package will be unsealed and the ID number of the drug will be cancelled. The drug manufacturer can use this system to grasp the flow and sales of the drug in order to adjust the production plan. Especially for special drugs or banned drugs management is more important. Innovation is mainly reflected in the innovation of technical solutions and technological application innovation: 1. Building a pharmaceutical network management and monitoring platform that applies modern network technology and radio frequency identification technology (RFID). Improve the scientific and technological content of special drug management, establish a drug management network system, and realize the functions of multi-cascade management, user inquiry and data processing of drugs. 2. The combination of the radio frequency identification device and the network single-chip computer constitutes an independent network data reading and writing device. The existing radio frequency identification system is connected to a PC through a serial port, and data exchange is carried out through a computer. In this project, if data exchange is carried out through a PC, a pharmacy will need a computer, which will increase the construction cost and operating cost, which will cause great The waste of the computer, and human interference to the computer will affect the normal operation of the system. The use of network single-chip microcomputer and radio frequency identification system for online data exchange will overcome the above-mentioned shortcomings. 3. Use this system to improve blood preparation management. According to regulations and evaluation requirements, medical institutions must know the type, use, and return status of blood preparations ordered for blood transfusion, record the flow of patients and save the batch number of blood used. If RFID technology is used for blood preparation management and full tracking, it can reduce the amount of manual work and reduce the error rate. 4. The application of this system can realize the medication management of doctors and patients, and improve the safety of medication. According to the statistics of the US Department of Health, the number of deaths caused by mistakes in the treatment of drugs exceeds the number of deaths caused by car accidents, breast cancer, and even AIDS. This is a serious warning sign. In the process of adjusting medicines and patients’ medications, the medical staff confirm the contents including: the adjustment of the medical and nursing operation department (such as patient identity, product name, dosage, quantity, double or even triple check of usage, etc.), and nursing staff’s identification of patients , Drugs, time, route of administration, injection site, injection rate and other work related to patient safety. Use RFID identification tags to improve medication safety. 5. Drug delivery and storage environmental condition monitoring and drug expiration management. Through the application of active radio frequency identification technology, the delivery and environmental condition monitoring can be achieved to ensure drug quality. According to foreign reports and preliminary verifications, radio frequency signals in the frequency band below low-power microwaves have no effect on most drugs, and the impact on drugs with biological activity needs to be further studied. The radio frequency identification device used in this application is a high-frequency and low-power device, conforms to the ISO14443A/15693 standard, will not cause any pollution or impact on the environment in which it is used, and conforms to the national safety and environmental protection policy.

work process

Radio Frequency Identification (RFID) applies modern technology to improve drug safety management, prevents counterfeit drugs, expired drugs, and banned drugs from entering the market, encourages “doctors and patients” to use drugs correctly, and curbs undesirable phenomena such as driving up drug prices and monopolizing the drug market.

The working principle of RFID can be divided into four steps: 1. The card reader sends out a certain frequency radio frequency signal through the antenna; 2. When the tag enters the magnetic field, it generates an induced current to obtain energy and sends information such as its own code to the card reader; 3. , The card reader collects information and decodes it; Fourth, the card reader sends the information data to the computer host for processing.

Scope of application of radio frequency identification (RFID) in drug management and its market outlook

Radio frequency tags can be issued by the drug inspection department together with the drug access number, and the drug manufacturer will be implanted in the drug package, and passed the hospital or “doctor-patient” verification to improve the tracking and safety management of the drug. The drug inspection department or the drug manufacturer It can dynamically control the flow and inventory of drugs, making drug management and inspection more scientific and timely.

The drug management system can be used for the safety supervision of drugs and chemical reagents, prevent counterfeit drugs, expired drugs, and illegal drugs from entering the market, encourage “medical and patient personnel” to use drugs correctly, and curb the occurrence of undesirable phenomena such as driving up drug prices and monopolizing the drug market. Therefore, Has a wide range of market applications.

Application of RFID in this field

Prevent counterfeit drugs from circulating on the market. The application of this technology has greatly improved the anti-counterfeiting technology of medicines. The identification numbers of medicines implanted with electronic tags will be stored in the medicine management database and cannot be modified by humans. Only genuine medicines can be identified by the system, which improves the anti-counterfeiting ability of medicines.

Monitoring of environmental conditions for drug transportation and storage. The drug undergoes safety tests during production, and its storage temperature, humidity, and other transportation and storage conditions are obtained. If the transportation and storage conditions do not meet the operating requirements, the drug will become invalid. Through active RFID applications, transportation and environmental conditions can be monitored to ensure the quality of medicines.

Drug validity management. Applying RFID technology to drug expiration management can reduce manpower, reduce unnecessary inventory waste, and improve drug management efficiency. Through the monitoring of the drug management database, the method of recalling expired drugs can be adopted to prevent medical accidents caused by expired drugs.

Improve drug safety. Through this system, “doctors and patients” can check the production date of the medicine, precautions for use, and comparison with similar medicines to improve the safety of medication. In hospitals, RFID cards can be worn to patients, and medicines can be automatically checked by the system to improve the correctness of medicines.

Blood preparation management. Blood preparations are one of the main ways for the spread of infectious diseases. The blood preparation can be managed by RFID to track and monitor its source, flow and usage, so as to improve work efficiency and management effects.

Management of special drugs and banned drugs. The management of special drugs and banned drugs is particularly important. Electronic tags can be affixed to the banned drugs of special drugs and the use rights can be added. For the transportation of these drugs, the GPRS function can be added on the basis of RFID technology to monitor and improve the whole process. The management level of special drugs and banned drugs.

Drug price management. Illegal vendors and certain hospitals use the market share of drugs or other reasons to drive up drug prices and seek huge profits, which greatly affects drug management and the rights and interests of consumers. Using this technology can make drug sales prices transparent and make consumption All rights and interests get the most fundamental guarantee.

Drug production and dynamic flow monitoring and macro. Through this system, the drugs sold can be queried dynamically and timely, the drug manufacturers can adjust the production and inventory of the drugs according to the obtained data, and the drug management department can macro-control the flow and flow of drugs. Improve its operational efficiency.

In the medical field, a large number of errors in prescriptions, drug delivery, and medication take place every year, leading to many medical accidents, a large number of lost hours and legal proceedings. According to statistics, the global annual loss in these aspects is as high as 75 billion US dollars. According to industry statistics, counterfeit and inferior drugs currently account for 10% of the global pharmaceutical market. Judging from the investigations conducted by the National Brand Enterprise Anti-counterfeiting Collaboration Network in the past two years, there are three development trends in the manufacture and sale of counterfeit drugs: First, the manufacture and sale of counterfeit counterfeit products are increasingly targeting brand-name best-selling drugs. In the cases that it cooperated with, there are more and more varieties of well-known companies such as Xi’an Janssen and Tianjin Sike, such as domperidone, dyconine, and Fenbid, because these drugs are not well-known in the market, or they are in demand. Big, and there is a lot of room for profit. The second is that fraudulent acts are becoming more and more concealed, and the methods are becoming more and more sophisticated. The various links of counterfeiting are scattered in various places, and each is responsible for one link. In the end, the counterfeit seller assembles the semi-finished products. Even if it is seized, it is only one link. The entire counterfeit chain will not “break the bones”, and As long as one place is investigated, all other links will soon be separated automatically, making the tracing work unable to proceed due to disconnection. The third is that counterfeiting methods, especially packaging and printing, are becoming more and more realistic, which is not only difficult for consumers to distinguish, but even for professional anti-counterfeiting personnel in enterprises. Local drug regulatory, public security and other law enforcement agencies have stepped up their crackdowns on the manufacture and sale of counterfeit and inferior drugs, and the order of the drug market has improved. In order to evade the crackdown by law enforcement agencies, the manufacture and sale of counterfeit products in the pharmaceutical market is becoming more and more concealed. Improved drug tracking methods may help hospitals save costs and curb the proliferation of counterfeit and inferior drugs.

RFID has great application potential in drug anti-counterfeiting and tracking and supply chain management. Its application scope includes investigating and combating counterfeit drugs, implementing efficient drug recalls, improving drug inventory management, detecting drug theft, identifying drugs entering illegal channels, etc. It can also be used to ensure the correct dispensing of medicines and improve the safety of medicines. The use of RFID technology will deter vendors who sell counterfeit drugs and dare not sell counterfeit drugs to unknowing wholesalers, pharmacists and patients. Since the medicines are tracked in every link of sales and their electronic resumes are recorded in the electronic database in real time, it can ensure that the medicines in the specific package are genuine and legal, and the pharmacist can also be sure of the safety and effectiveness of the medicines dispensed. ; At the same time, electronic tracking and tracing technology provides drug sellers with confidence that they can be sure of the safety and effectiveness of the drugs they sell, and there is no need to increase sales costs to ensure the safety and effectiveness of the drugs during sales. This will be a key motivation for drug manufacturers to adopt RFID. my country’s market for realizing drug management with radio frequency identification technology is still blank, and its application has a large market space.

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